Search

This Phase III, multicenter, double-blind, placebo-controlled treat-through study will evaluate the efficacy and safety of induction and maintenance therapy with Afimkibart (also known as RO7790121) in participants with moderately to severely active Crohn's disease (CD).

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 374 sites in total

The purpose of this study is to evaluate how-well icotrokinra works (clinical efficacy) and how safe it is (safety) in participants with moderately to severely active Crohn's disease (CD; a long-term condition causing severe inflammation of the intestinal tract).

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 370 sites in total

This Phase III, multicenter, double-blind, placebo-controlled study will evaluate the efficacy and safety of induction therapy with Afimkibart (RO7790121) compared with placebo in participants with moderately to severely active ulcerative colitis (UC).

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 200 sites in total

This is a 26-week, multi-center, randomized, double-blind, placebo-controlled study with a 4-week treatment-free Safety Follow-up period to assess the safety and efficacy of tenapanor (5 mg, 25mg, and 50 mg) in adult patients with Chronic Idiopathic Constipation (CIC) when administered twice daily f…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 109 sites in total · contact listed

To evaluate the safety and efficacy of the ProTractX3™ DCB for the treatment of benign esophageal strictures.

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 34 sites in total · contact listed

Ulcerative colitis is a long-lasting condition that causes swelling and sores in the large intestine. This study tests whether a small device placed under the skin can help reduce bowel urgency in people with ulcerative colitis. The investigational device sends mild signals to a nerve near the tailb…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 19 sites in total · contact listed

Ulcerative Colitis (UC) and Crohn's Disease (CD) are long-term conditions in the gut that can cause diarrhea, swelling (inflammation), bleeding from the anus, and belly pain. The main aim of this study is to check for how many participants with UC and CD signs and symptoms disappear after 3.5 months…

✓ Contact✗ Claimed

📍 Nearest site: Hutchinson, Kansas, United States — 36 km away · 101 sites in total · contact listed

This is a multi-center evaluation of efruxifermin (EFX) in a randomized, double-blind, placebo-controlled study in subjects with non-cirrhotic NASH/MASH and fibrosis stage 2 or 3 (F2 or F3). The study will enroll subjects in two cohorts for a total samples size of 1650 subjects.

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 356 sites in total

The main purpose of the SYNERGY-OUTCOMES study is to find out whether retatrutide and tirzepatide can prevent major adverse liver outcomes (MALO) in people with high-risk metabolic dysfunction-associated steatotic liver disease (MASLD). The study will enroll adults who have MASLD based on non-invasi…

✓ Contact✗ Claimed

📍 Nearest site: El Dorado, Kansas, United States — 85 km away · 563 sites in total · contact listed

To determine the safety and efficacy of GIE Medical's ProTractX3™ TTS DCB for the treatment of recurrent benign bowel strictures.

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 33 sites in total · contact listed

The Shield post-approval study (PAS) is a prospective, longitudinal study supplemented with Real World Evidence (RWE) to evaluate the longitudinal performance of Shield in an average risk population at a second round of testing for individuals between the ages of 45 and 81 at average risk of CRC usi…

✓ Contact✗ Claimed

📍 Nearest site: Hutchinson, Kansas, United States — 36 km away · 69 sites in total

This phase II study evaluates how well pemigatinib works for the treatment of adult patients with pancreatic cancer that has spread from where it first started to nearby tissue, lymph nodes, or distant parts of the body (advanced) or has spread from where it first started to other places in the body…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 109 sites in total · contact listed

The overall objective of the RESTORATiVE303 study is to evaluate the safety and the Clostridioides difficile infection (CDI) recurrence rate at Week 8 in participants who receive a 14-day course of VE303 or matching placebo. The objectives and endpoints are identical for Stage 1 (recurrent CDI) and…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 215 sites in total

This trial examines colorectal cancer incidence in participants with 1 to 2 non-advanced adenomas randomized to surveillance colonoscopy at 10 years compared to participants randomized to surveillance colonoscopy at 5 and 10 years.

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 493 sites in total · contact listed

This Phase II/III trial will evaluate the what kind of chemotherapy to recommend to patients based on the presence or absences of circulating tumor DNA (ctDNA) after surgery for colon cancer.

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 1,077 sites in total · contact listed

This is a randomized, double-blind, placebo-controlled basket trial evaluating mifomelatide (TCMCB07) administered daily by subcutaneous (SC) injection in up to 120 patients. Patients will be enrolled into two cohorts 1) patients with newly diagnosed, advanced, unresectable colorectal cancer (CRC) o…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 26 sites in total · contact listed

The objective of this registry is to gather clinical data on symptomatic patients with mitral valve disease, including patients with mitral regurgitation, mitral stenosis, and mixed mitral valve disease. Data collected from this registry are expected to improve our understanding of the impact of cor…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 24 sites in total · contact listed

This study collects blood and tissue samples from patients with cancer and without cancer to evaluate tests for early cancer detection. Collecting and storing samples of blood and tissue from patients with and without cancer to study in the laboratory may help researchers develop tests for the early…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 745 sites in total · contact listed

The purpose of this study is to compare how long the participants are disease-free (progression-free survival) when treated with amivantamab and chemotherapy with 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovorin, oxaliplatin (mFOLFOX6) or 5-fluorouracil, leucovorin calcium (folini…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 239 sites in total

The purpose of the study is to learn about how effective, safe, and tolerable the Clostridioides difficile (C. difficile) vaccine is in decreasing the number of C. difficile infections (pCDI) in adults 65 years of age or older. The participants will receive either the C. difficile vaccine or placeb…

✓ Contact✗ Claimed

📍 Nearest site: Newton, Kansas, United States — 53 km away · 185 sites in total

The purpose of this study is to compare how long the participants are disease-free (progression-free survival) and and the length of time until a participant dies (overall survival), when treated with amivantamab and chemotherapy with 5-fluorouracil, leucovorin calcium (folinic acid) or levoleucovor…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 251 sites in total

Migraine is a common neurological disorder typically characterized by attacks of throbbing, moderate to severe headache, often associated with nausea, vomiting, and sensitivity to light and sound. Migraine is extremely common and disabling in children. The purpose of this study is to evaluate how sa…

✓ Contact✗ Claimed

📍 Nearest site: Wichita, Kansas, United States — 43 km away · 129 sites in total

Blood sugar levels are controlled by insulin, a hormone made by cells in the pancreas. After a meal, carbohydrates are broken down into glucose which is absorbed from the intestine into the blood leading to a rise in glucose (blood sugar) which triggers the secretion of insulin. Insulin binds to cel…

✓ Contact✗ Claimed

📍 Nearest site: El Dorado, Kansas, United States — 85 km away · 25 sites in total · contact listed